The 2nd 2024 MeetUp hosted by the Mandic Hub highlights innovations in the use of stem cells
The second Mandic Hub MeetUp took place on Wednesday, March 27, at the entrance to Block M of São Leopoldo Mandic College. This monthly event aims to foster dialogue between companies and students on topics related to dentistry and medicine.
The theme of this edition was “Innovations in the Use of Stem Cells: The Experience at the Kennedy Space Center,” featuring Prof. Dr. André Pelegrine, a faculty member at the institution, and José Ricardo Muniz Ferreira, CEO of R-Crio Células-Tronco. The discussion was moderated by Prof. Dr. Victor Montalli.
During the meeting, Pelegrine and Muniz explained the research conducted at the space sciences laboratory located in Florida, USA. The study investigated the activity of stem cells under different conditions of microgravity and oxygenation.
Muniz began the discussion by explaining the project’s origins: “The initiative began a few years ago through a partnership between R-Crio and the KSCIA International Space Academy, known for its study programs that include Brazilian researchers. I had the opportunity to meet the program’s leaders, which led to this partnership.”
When explaining the challenges faced in the research, Muniz noted: “Once we decided to work with stem cells, the next step was to choose the source. We opted for the periosteum because it is an interesting tissue to work with and can be collected without a moistened source. However, we were confronted with human physiology. We humans have adaptations to gravity and negative reactions in bone tissue, which place greater demands on the mechanical aspects. Without this pressure, the absence of gravity results in a process very similar to osteoporosis and osteoarthritis.”
In addition, Pelegrine emphasized that the research will benefit space missions, in which crew members require special care during extended voyages: “Any trauma, no matter how minor, can easily result in a major fracture, especially over long distances. Therefore, we are working on regenerative medicine to accelerate the healing process.”
Finally, André Pelegrine explained that the research extends to regions beyond the Kennedy Space Center, including Brazil. He also noted that the research was only possible thanks to the trust placed in him by São Leopoldo Mandic College, which supported the project and made it possible. Check out the photos below:
