The Professional Master’s Degree in Dentistry with a Concentration in Dentistry for Patients with Special Needs at São Leopoldo Mandic College aims to provide an update on the key concepts related to systemic, neurological, and special conditions, as well as the protocols relevant to each specific condition, and to provide dental surgeons with a clear understanding of the basic technical and pharmacological care required when treating patients with complex health conditions who require special care in the dental setting. In compromised patients, the oral cavity may be filled with manifestations that could reflect the medical, systemic, neurological, or special condition the patient is experiencing. The program aims to train highly competent professionals for innovative and transformative dentistry. In addition to preparing students for research and community outreach, the program equips professionals to develop innovative technical products and encourages participation in educational projects, contributing to advancements in the field across various contexts.